RANKL/RANK: from bone loss to the prevention of breast cancer
RANK and RANKL, a receptor ligand pair belonging to the tumour necrosis factor family, are the critical regulators of osteoclast development and bone metabolism. Besides their essential function in bone, RANK and RANKL have also been identified as the key factors for the formation of a lactating mam...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
The Royal Society
2016-01-01
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Series: | Open Biology |
Subjects: | |
Online Access: | https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.160230 |