Characterization of Chronic Cutaneous Lesions from TNF-Receptor-1-Deficient Mice Infected by Leishmania major

Characterization of Chronic Cutaneous Lesions from TNF-Receptor-1-Deficient Mice Infected by Leishmania major

Leishmania major-infected TNF receptor 1 deficient (TNFR1 KO) mice resolve parasitism but fail to resolve lesions, while wild-type mice completely heal. We investigated the cell composition, cytokine production, and apoptosis in lesions from L. major-infected TNFR1 KO and wild-type (WT) mice. Chroni...

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Bibliographic Details
Main Authors: Carolina Ferreira Oliveira, Daniel Manzoni-de-Almeida, Paula Seixas Mello, Caio Cotta Natale, Helton da Costa Santiago, Luíza da Silva Miranda, Fernanda Oliveira Ferraz, Liliane Martins dos Santos, Mauro Martins Teixeira, Rosa Maria Esteves Arantes, Leda Quercia Vieira
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2012/865708

Internet

http://dx.doi.org/10.1155/2012/865708

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