Prevention of low density lipoprotein aggregation by high density lipoprotein or apolipoprotein A-I.

We have shown previously that low density lipoprotein (LDL) subjected to vortexing forms self-aggregates that are avidly phagocytosed by macrophages. That phagocytic uptake is mediated by the LDL receptor. We now show that LDL self-aggregation is strongly inhibited (80-95%) by the presence of high d...

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Bibliographic Details
Main Authors: JC Khoo, E Miller, P McLoughlin, D Steinberg
Format: Article
Language:English
Published: Elsevier 1990-04-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520428329