Exceptional Longevity and Polygenic Risk for Cardiovascular Health

Exceptional Longevity and Polygenic Risk for Cardiovascular Health

Studies investigating exceptionally long-lived (ELL) individuals, including genetic studies, have linked cardiovascular-related pathways, particularly lipid and cholesterol homeostasis, with longevity. This study explored the genetic profiles of ELL individuals (cases: n = 294, 95–106 year...

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Bibliographic Details
Main Authors: Mary Revelas, Anbupalam Thalamuthu, Christopher Oldmeadow, Tiffany-Jane Evans, Nicola J. Armstrong, Carlos Riveros, John B. Kwok, Peter R. Schofield, Henry Brodaty, Rodney J. Scott, John R. Attia, Perminder S. Sachdev, Karen A. Mather
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Genes
Subjects:
polygenic risk score
cardiovascular health
exceptional longevity
lipid profile
Online Access:http://www.mdpi.com/2073-4425/10/3/227

Internet

http://www.mdpi.com/2073-4425/10/3/227

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