Galectin-3 up-regulation in hypoxic and nutrient deprived microenvironments promotes cell survival.

Galectin-3 up-regulation in hypoxic and nutrient deprived microenvironments promotes cell survival.

Galectin-3 (gal-3) is a β-galactoside binding protein related to many tumoral aspects, e.g. angiogenesis, cell growth and motility and resistance to cell death. Evidence has shown its upregulation upon hypoxia, a common feature in solid tumors such as glioblastoma multiformes (GBM). This tumor prese...

Full description

Bibliographic Details
Main Authors: Rafael Yamashita Ikemori, Camila Maria Longo Machado, Karina Mie Furuzawa, Suely Nonogaki, Eduardo Osinaga, Kazuo Umezawa, Marcelo Alex de Carvalho, Liana Verinaud, Roger Chammas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4219723?pdf=render

Internet

http://europepmc.org/articles/PMC4219723?pdf=render

Similar Items