Extracellular vesicle-mediated macrophage activation: An insight into the mechanism of thioredoxin-mediated immune activation

Extracellular vesicle-mediated macrophage activation: An insight into the mechanism of thioredoxin-mediated immune activation

Extracellular vesicles (EVs) generated from redox active anticancer drugs are released into the extracellular environment. These EVs contain oxidized molecules and trigger inflammatory responses by macrophages. Using a mouse model of doxorubicin (DOX)-induced tissue injury, we previously found that...

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Bibliographic Details
Main Authors: Chontida Yarana, Hannah Thompson, Luksana Chaiswing, D. Allan Butterfield, Heidi Weiss, Subbarao Bondada, Sara Alhakeem, Suriyan Sukati, Daret K. St. Clair
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231719301661

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http://www.sciencedirect.com/science/article/pii/S2213231719301661

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