Isolation methodology is essential to the evaluation of the extracellular vesicle component of the senescence‐associated secretory phenotype

Isolation methodology is essential to the evaluation of the extracellular vesicle component of the senescence‐associated secretory phenotype

Abstract A hallmark of senescence is the acquisition of an enhanced secretome comprising inflammatory mediators and tissue remodelling agents – the senescence‐associated secretory phenotype (SASP). Through the SASP, senescent cells are hypothesised to contribute to both ageing and pathologies associ...

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Bibliographic Details
Main Authors: Ryan Wallis, Natasa Josipovic, Hannah Mizen, Arturo Robles‐Tenorio, Eleanor J. Tyler, Argyris Papantonis, Cleo L. Bishop
Format: Article
Language:English
Published: Taylor & Francis Group 2021-02-01
Series:Journal of Extracellular Vesicles
Subjects:
ageing
exosomes
extracellular vesicles
paracrine senescence
senescence‐associated secretory phenotype
senescence
Online Access:https://doi.org/10.1002/jev2.12041

Internet

https://doi.org/10.1002/jev2.12041

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