Time-resolved human kinome RNAi screen identifies a network regulating mitotic-events as early regulators of cell proliferation.

Analysis of biological processes is frequently performed with the help of phenotypic assays where data is mostly acquired in single end-point analysis. Alternative phenotypic profiling techniques are desired where time-series information is essential to the biological question, for instance to diffe...

Full description

Bibliographic Details
Main Authors: Jitao David Zhang, Cindy Koerner, Stephanie Bechtel, Christian Bender, Ioanna Keklikoglou, Christian Schmidt, Anja Irsigler, Ute Ernst, Ozgür Sahin, Stefan Wiemann, Ulrich Tschulena
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3135613?pdf=render