Influence of patient characteristics on chimeric antigen receptor T cell therapy in B-cell acute lymphoblastic leukemia

Influence of patient characteristics on chimeric antigen receptor T cell therapy in B-cell acute lymphoblastic leukemia

CAR T therapy has some efficacy in the treatment of patients with refractory/relapsed B-cell acute lymphoblastic leukemia; however in some patients further relapse is encountered. Here, the authors conduct a Phase II clinical trial of a CD19 CAR T and demonstrate that patients with extramedullary di...

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Bibliographic Details
Main Authors: Furun An, Huiping Wang, Zhenyun Liu, Fan Wu, Jiakui Zhang, Qianshan Tao, Yingwei Li, Yuanyuan Shen, Yanjie Ruan, Qing Zhang, Ying Pan, Weiwei Zhu, Hui Qin, Yansheng Wang, Yongling Fu, Zhenqing Feng, Zhimin Zhai
Format: Article
Language:English
Published: Nature Publishing Group 2020-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19774-x

Internet

https://doi.org/10.1038/s41467-020-19774-x

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