Guide RNA Repertoires in the Main Lineages of Trypanosoma cruzi: High Diversity and Variable Redundancy Among Strains

Trypanosoma cruzi, as other kinetoplastids, has a complex mechanism of editing of mitochondrial mRNAs that requires guide RNAs (gRNAs) coded in DNA minicircles in the kinetoplast. There are many variations on this mechanism among species. mRNA editing and gRNA repertoires are almost unknown in T. cr...

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Bibliographic Details
Main Authors: Fanny Rusman, Noelia Floridia-Yapur, Nicolás Tomasini, Patricio Diosque
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
DTU
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.663416/full