Adiponectin receptor 2 deficiency results in reduced atherosclerosis in the brachiocephalic artery in apolipoprotein E deficient mice.

Adiponectin has been shown to have beneficial cardiovascular effects and to signal through the adiponectin receptors, AdipoR1 and AdipoR2. The original aim of this study was to investigate the effect of combined AdipoR1 and AdipoR2 deficiency (AdipoR1(-/-)AdipoR2(-/-)) on atherosclerosis. However, w...

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Bibliographic Details
Main Authors: Anna Lindgren, Malin Levin, Sandra Rodrigo Blomqvist, Johannes Wikström, Andrea Ahnmark, Christina Mogensen, Gerhard Böttcher, Mohammad Bohlooly-Y, Jan Borén, Li-Ming Gan, Daniel Lindén
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3855811?pdf=render