CYP2A6 gene polymorphisms impact to nicotine metabolism
<p>Nicotine is a major addictive compound in tobacco cigarette smoke. After being absorbed by the lung nicotine is rapidly metabolized and mainly inactivated to cotinine by hepatic cytochrome P450 2A6 (CYP2A6) enzyme. Genetic polymorphisms in CYP2A6 may play a role in smoking behavior and nico...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Faculty of Medicine Universitas Indonesia
2010-02-01
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| Series: | Medical Journal of Indonesia |
| Online Access: | http://mji.ui.ac.id/journal/index.php/mji/article/view/377 |