Cocaine Inhibition of Nicotinic Acetylcholine ReceptorsInfluences Dopamine Release

Cocaine Inhibition of Nicotinic Acetylcholine ReceptorsInfluences Dopamine Release

Nicotinic acetylcholine receptors (nAChRs) potently regulate dopamine (DA) release in the striatum and alter cocaine’s ability to reinforce behaviors. Since cocaine is a weak nAChR inhibitor, we hypothesized that cocaine may alter DA release by inhibiting the nAChRs in DA terminals in the striatum a...

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Bibliographic Details
Main Authors: Alexandra eAcevedo-Rodriguez, Lifen eZhang, Fuwen eZhou, Suzhen eGong, Howard eGu, Mariella eDe Biasi, Fu-Ming eZhou, John A. Dani
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
Substantia Nigra
Ventral Tegmental Area
Addiction
Striatum
Voltammetry
mesolimbic
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnsyn.2014.00019/full

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http://journal.frontiersin.org/Journal/10.3389/fnsyn.2014.00019/full

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