Aerobic exercise regulates Rho/cofilin pathways to rescue synaptic loss in aged rats.

PURPOSE:The role of exercise to prevent or reverse aging-induced cognitive decline has been widely reported. This neuroprotection is associated with changes in the synaptic structure plasticity. However, the mechanisms of exercise-induced synaptic plasticity in the aging brain are still unclear. Thu...

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Bibliographic Details
Main Authors: Yan Li, Li Zhao, Boya Gu, Jiajia Cai, Yuanyuan Lv, Laikang Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5289643?pdf=render