Regulatory T Cells Promote Apelin-Mediated Sprouting Angiogenesis in Type 2 Diabetes

Summary: The role of CD4+ T cells in the ischemic tissues of T2D patients remains unclear. Here, we report that T2D patients’ vascular density was negatively correlated with the number of infiltrating CD4+ T cells after ischemic injury. Th1 was the predominant subset, and Th1-derived IFN-γ and TNF-α...

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Bibliographic Details
Main Authors: Oscar M. Leung, Jiatao Li, Xisheng Li, Vicken W. Chan, Kevin Y. Yang, Manching Ku, Lu Ji, Hao Sun, Herman Waldmann, Xiao Yu Tian, Yu Huang, James Lau, Bin Zhou, Kathy O. Lui
Format: Article
Language:English
Published: Elsevier 2018-08-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718311094