Withaferin A inhibits the proteasome activity in mesothelioma in vitro and in vivo.

Withaferin A inhibits the proteasome activity in mesothelioma in vitro and in vivo.

The medicinal plant Withania somnifera has been used for over centuries in Indian Ayurvedic Medicine to treat a wide spectrum of disorders. Withaferin A (WA), a bioactive compound that is isolated from this plant, has anti-inflammatory, immuno-modulatory, anti-angiogenic, and anti-cancer properties....

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Bibliographic Details
Main Authors: Huanjie Yang, Ying Wang, Vino T Cheryan, Wenjuan Wu, Cindy Qiuzhi Cui, Lisa A Polin, Harvey I Pass, Q Ping Dou, Arun K Rishi, Anil Wali
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3422308?pdf=render

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http://europepmc.org/articles/PMC3422308?pdf=render

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