Crystal structure of Plasmodium knowlesi apical membrane antigen 1 and its complex with an invasion-inhibitory monoclonal antibody.

The malaria parasite Plasmodium knowlesi, previously associated only with infection of macaques, is now known to infect humans as well and has become a significant public health problem in Southeast Asia. This species should therefore be targeted in vaccine and therapeutic strategies against human m...

Full description

Bibliographic Details
Main Authors: Brigitte Vulliez-Le Normand, Bart W Faber, Frederick A Saul, Marjolein van der Eijk, Alan W Thomas, Balbir Singh, Clemens H M Kocken, Graham A Bentley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4401722?pdf=render