Structural and electronic determinants of lytic polysaccharide monooxygenase reactivity on polysaccharide substrates

Structural and electronic determinants of lytic polysaccharide monooxygenase reactivity on polysaccharide substrates

Copper-dependent lytic polysaccharide monooxygenases (LPMOs) oxidatively cleave polysaccharides. Here the authors present a structure-function characterization of fungal LPMOs, showing that a particular LPMO cleaves xylan using a mechanism that involves an alternative copper coordination geometry.

Bibliographic Details
Main Authors: T. J. Simmons, K. E. H. Frandsen, L. Ciano, T. Tryfona, N. Lenfant, J. C. Poulsen, L. F. L. Wilson, T. Tandrup, M. Tovborg, K. Schnorr, K. S. Johansen, B. Henrissat, P. H. Walton, L Lo Leggio, P. Dupree
Format: Article
Language:English
Published: Nature Publishing Group 2017-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01247-3

Internet

https://doi.org/10.1038/s41467-017-01247-3

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