PROP1 overexpression in corticotrophinomas: evidence for the role of PROP1 in the maintenance of cells committed to corticotrophic differentiation

OBJECTIVE: The expression of transcription factors involved in early pituitary development, such as PROP1 and POU1F1, has been detected in pituitary adenoma tissues. In this study, we sought to characterize the transcriptional profiles of PROP1, POU1F1, and TBX19 in functioning and nonfunctioning pi...

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Main Authors: Ricardo V. Araujo, Claudia V. Chang, Valter A. S. Cescato, Maria Candida B. V. Fragoso, Marcello D. Bronstein, Berenice B. Mendonca, Ivo J. P. Arnhold, Luciani R. S. Carvalho
Format: Article
Language:English
Published: Faculdade de Medicina / USP 2013-06-01
Series:Clinics
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322013000600887