Tegafur-induced acral hyperpigmentation

Tegafur is a prodrug of 5-fluorouracil (5-FU) with a similar spectrum of antitumor activity. It is used in the treatment of advanced gastrointestinal neoplasms. Over 5-FU, tegafur has the advantage of oral administration and less hematologic toxicity. Gastrointestinal toxicity is its main dose-limit...

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Bibliographic Details
Main Authors: Vera Teixeira, Ricardo Vieira, Américo Figueiredo
Format: Article
Language:English
Published: PAGEPress Publications 2011-09-01
Series:Dermatology Reports
Subjects:
Online Access:http://www.pagepress.org/journals/index.php/dr/article/view/3332