Characterization of the Blood Brain Barrier Disruption in the Photothrombotic Stroke Model

Characterization of the Blood Brain Barrier Disruption in the Photothrombotic Stroke Model

Blood brain barrier (BBB) damage is an important pathophysiological feature of ischemic stroke which significantly contributes to development of severe brain injury and therefore is an interesting target for therapeutic intervention. A popular permanent occlusion model to study long term recovery fo...

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Bibliographic Details
Main Authors: Rebecca Z. Weber, Lisa Grönnert, Geertje Mulders, Michael A. Maurer, Christian Tackenberg, Martin E. Schwab, Ruslan Rust
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Physiology
Subjects:
photothrombotic stroke
BBB
ischemia
leakage
edema
pericytes
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2020.586226/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2020.586226/full

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