Cryptococcus neoformans is resistant to surfactant protein A mediated host defense mechanisms.

Initiation of a protective immune response to infection by the pathogenic fungus Cryptococcus neoformans is mediated in part by host factors that promote interactions between immune cells and C. neoformans yeast. Surfactant protein A (SP-A) contributes positively to pulmonary host defenses against a...

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Bibliographic Details
Main Authors: Steven S Giles, Aimee K Zaas, Mike F Reidy, John R Perfect, Jo Rae Wright
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2147053?pdf=render