LPS induces IL-10 production by human alveolar macrophages via MAPKinases- and Sp1-dependent mechanisms

<p>Abstract</p> <p>Background</p> <p>IL-10 is a cytokine mainly produced by macrophages that plays key roles in tolerance to inhaled antigens and in lung homeostasis. Its regulation in alveolar macrophages (HAM), the resident lung phagocytes, remains however unknown.<...

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Bibliographic Details
Main Authors: Pilette Charles, Guisset Amélie C, Chanteux Hugues, Sibille Yves
Format: Article
Language:English
Published: BMC 2007-10-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/8/1/71