Impaired Cerebellum to Primary Motor Cortex Associative Plasticity in Parkinson’s Disease and Spinocerebellar Ataxia Type 3

BackgroundFunctional perturbation of the cerebellum (CB)–motor cortex (M1) interactions may underlie pathophysiology of movement disorders, such as Parkinson’s disease (PD) and spinocerebellar ataxia type 3 (SCA3). Recently, M1 motor excitability can be bidirectionally modulated in young subjects by...

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Bibliographic Details
Main Authors: Ming-Kuei Lu, Jui-Cheng Chen, Chun-Ming Chen, Jeng-Ren Duann, Ulf Ziemann, Chon-Haw Tsai
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Neurology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fneur.2017.00445/full