Detachment Activated CyPA/CD147 Induces Cancer Stem Cell Potential in Non-stem Breast Cancer Cells

Detachment Activated CyPA/CD147 Induces Cancer Stem Cell Potential in Non-stem Breast Cancer Cells

BackgroundCancer stem cells (CSCs), responsible for cancer metastasis and recurrence, are generated from non-CSCs after chemo-radiation therapy. This study investigated the induction of CSC potential in non-stem breast cancer cells and the underlying molecular mechanisms in detachment culture.Method...

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Bibliographic Details
Main Authors: Yao Meng, Li-Jun Yang, Bao-Qing Xu, Duo He, Zhe Xu, Dong Wu, Bin Wang, Hong-Yong Cui, Shi-Jie Wang, Li-Juan Wang, Xiao-Qing Wu, Jian-Li Jiang, Liang Xu, Zhi-Nan Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
breast cancer
detachment culture
induced cancer stem cells
CD147
CyPA
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.543856/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.543856/full

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