Coordination of Rheb lysosomal membrane interactions with mTORC1 activation [version 1; peer review: 4 approved]
A complex molecular machinery converges on the surface of lysosomes to ensure that the growth-promoting signaling mediated by mechanistic target of rapamycin complex 1 (mTORC1) is tightly controlled by the availability of nutrients and growth factors. The final step in this activation process is dep...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
F1000 Research Ltd
2020-05-01
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| Series: | F1000Research |
| Online Access: | https://f1000research.com/articles/9-450/v1 |