De-escalation of radiation therapy in patients with stage I, node-negative, HER2-positive breast cancer

Abstract In the modern era, highly effective anti-HER2 therapy is associated with low local-regional recurrence (LRR) rates for early-stage HER2+ breast cancer raising the question of whether local therapy de-escalation by radiation omission is possible in patients with small-node negative tumors tr...

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Bibliographic Details
Main Authors: Jose G. Bazan, Sachin R. Jhawar, Daniel Stover, Ko Un Park, Sasha Beyer, Erin Healy, Julia R. White
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-021-00242-8