Cyclic mechanical strain causes cAMP-response element binding protein activation by different pathways in cardiac fibroblasts
The transcription factor cAMP-response element binding protein (CREB) mediates the mechanical strain-induced gene expression in the heart. This study investigated which signaling pathways are involved in the strain-induced CREB activation using cultured ventricular fibroblasts from adult rat hearts....
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Touch Medical Media
2010-02-01
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| Series: | Heart International |
| Subjects: | |
| Online Access: | http://www.pagepress.org/journals/index.php/hi/article/view/1032 |