Siphonocholin isolated from red sea sponge Siphonochalina siphonella attenuates quorum sensing controlled virulence and biofilm formation

Siphonocholin isolated from red sea sponge Siphonochalina siphonella attenuates quorum sensing controlled virulence and biofilm formation

Increasing incidence of multi-drug resistant bacterial pathogens, especially in clinical settings, has been developed into a grave health situation. The drug resistance problem demands the necessity for alternative unique therapeutic policies. One such tactic is targeting the quorum sensing (QS) con...

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Bibliographic Details
Main Authors: Perwez Alam, Ali S. Alqahtani, Fohad Mabood Husain, Md. Tabish Rehman, Mohamed F. Alajmi, Omar M. Noman, Ali A. El Gamal, Shaza M. Al-Massarani, Mohammad Shavez Khan
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Saudi Pharmaceutical Journal
Subjects:
Siphonochalina siphonella
Siphonocholin
Red sea sponge
Antipathogenic Quorum sensing
Biofilm
Molecular docking and simulation
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016420302085

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http://www.sciencedirect.com/science/article/pii/S1319016420302085

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