Protective Effect of Piceatannol Against Acute Lung Injury Through Protecting the Integrity of Air-Blood Barrier and Modulating the TLR4/NF-κB Signaling Pathway Activation

Protective Effect of Piceatannol Against Acute Lung Injury Through Protecting the Integrity of Air-Blood Barrier and Modulating the TLR4/NF-κB Signaling Pathway Activation

Acute lung injury (ALI) is a common and complex inflammatory lung syndrome with higher morbidity and mortality rate. Piceatannol (PIC) has anti-inflammation and anti-oxidant properties. The study was designed to explore the effect and the action mechanisms of PIC on lipopolysaccharide (LPS)-induced...

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Bibliographic Details
Main Authors: Lu-Yuan Peng, Meng Yuan, Hai-Tao Shi, Jing-He Li, Ke Song, Jiang-Ni Huang, Peng-Fei Yi, Ben-Dong Fu, Hai-Qing Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Pharmacology
Subjects:
acute lung injury
lipopolysaccharide
piceatannol
air-blood barrier
TLR4/NF-κB
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01613/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.01613/full

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