A Gprc5a Tumor Suppressor Loss of Expression Signature Is Conserved, Prevalent, and Associated with Survival in Human Lung Adenocarcinomas

Increasing the understanding of the impact of changes in oncogenes and tumor suppressor genes is essential for improving the management of lung cancer. Recently, we identified a new mouse lung-specific tumor suppressor—the G protein-coupled receptor 5A (Gprc5a). Microarray analysis of the transcrip...

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Bibliographic Details
Main Authors: Humam Kadara, Junya Fujimoto, Taoyan Men, Xiaofeng Ye, Dafna Lotan, Ju-Seog Lee, Reuben Lotan
Format: Article
Language:English
Published: Elsevier 2010-06-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558610800077