Rotational restriction of nascent peptides as an essential element of co-translational protein folding: possible molecular players and structural consequences
Abstract Background A basic tenet of protein science is that all information about the spatial structure of proteins is present in their sequences. Nonetheless, many proteins fail to attain native structure upon experimental denaturation and refolding in vitro, raising the question of the specific r...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2017-05-01
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| Series: | Biology Direct |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13062-017-0186-1 |