Methylation Profile of Von Hipple Lindau Gene Promoter in Acute Lymphoblastic Leukemia Patients

Background: DNA methylation is an epigenetic mechanism that often modifies the function of genes and affects gene expression, which may sometimes lead to cancerdevelopment. Tumor suppressor genes such as VHL (Von Hippel-Lindau) may besilenced when affected by epigenetic alteration. This study inves...

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Bibliographic Details
Main Authors: Samaneh Ahmadi, Shaban Alizadeh, Fatemeh Nadali, Sasan Ghaffari, Mehdi Azad
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2018-05-01
Series:Basic & Clinical Cancer Research
Subjects:
Online Access:https://bccr.tums.ac.ir/index.php/bccrj/article/view/277