Methylation Profile of Von Hipple Lindau Gene Promoter in Acute Lymphoblastic Leukemia Patients
Background: DNA methylation is an epigenetic mechanism that often modifies the function of genes and affects gene expression, which may sometimes lead to cancerdevelopment. Tumor suppressor genes such as VHL (Von Hippel-Lindau) may besilenced when affected by epigenetic alteration. This study inves...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Tehran University of Medical Sciences
2018-05-01
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Series: | Basic & Clinical Cancer Research |
Subjects: | |
Online Access: | https://bccr.tums.ac.ir/index.php/bccrj/article/view/277 |