Long-chain fatty acid combustion rate is associated with unique metabolite profiles in skeletal muscle mitochondria.

Incomplete or limited long-chain fatty acid (LCFA) combustion in skeletal muscle has been associated with insulin resistance. Signals that are responsive to shifts in LCFA beta-oxidation rate or degree of intramitochondrial catabolism are hypothesized to regulate second messenger systems downstream...

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Bibliographic Details
Main Authors: Erin L Seifert, Oliver Fiehn, Véronic Bezaire, David R Bickel, Gert Wohlgemuth, Sean H Adams, Mary-Ellen Harper
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2844415?pdf=render