Hypoxia regulates human mast cell adhesion to fibronectin via the PI3K/AKT signaling pathway

Hypoxia regulates human mast cell adhesion to fibronectin via the PI3K/AKT signaling pathway

A decrease in oxygen concentration is a hallmark of inflammatory reactions resulting from infection or homeostasis disorders. Mast cells interact with extracellular matrix and other cells by adhesion receptors. We investigated the effect of hypoxia on integrin-mediated mast cell adhesion to fibronec...

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Bibliographic Details
Main Authors: Joanna Pastwińska, Aurelia Walczak-Drzewiecka, Magdalena Łukasiak, Marcin Ratajewski, Jarosław Dastych
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Cell Adhesion & Migration
Subjects:
mast cells
lad2
adhesion
fibronectin
integrin α5β1
hypoxia
scf
pi3k
akt
wortmannin
Online Access:http://dx.doi.org/10.1080/19336918.2020.1764690

Internet

http://dx.doi.org/10.1080/19336918.2020.1764690

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