Kinetic Basis of the Bifunctionality of SsoII DNA Methyltransferase

Kinetic Basis of the Bifunctionality of SsoII DNA Methyltransferase

Type II restriction–modification (RM) systems are the most widespread bacterial antiviral defence mechanisms. DNA methyltransferase SsoII (M.SsoII) from a Type II RM system SsoII regulates transcription in its own RM system in addition to the methylation function. DNA with a so-called regulatory sit...

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Bibliographic Details
Main Authors: Nadezhda A. Timofeyeva, Alexandra Yu. Ryazanova, Maxim V. Norkin, Tatiana S. Oretskaya, Olga S. Fedorova, Elena A. Kubareva
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Molecules
Subjects:
restriction–modification system
DNA methyltransferase
enzyme kinetics
pre-steady-state kinetics
stopped-flow assay
transcription factor
Online Access:http://www.mdpi.com/1420-3049/23/5/1192

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http://www.mdpi.com/1420-3049/23/5/1192

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