The dermato-protective effects of lucidone from Lindera erythrocarpa through the induction of Nrf2-mediated antioxidant genes in UVA-irradiated human skin keratinocytes

The dermato-protective effects of lucidone from Lindera erythrocarpa through the induction of Nrf2-mediated antioxidant genes in UVA-irradiated human skin keratinocytes

This study investigated the dermato-protective effects of lucidone, a cyclopentenedione from Lindera erythrocarpa dried fruits, against UVA-induced oxidative stress and apoptosis in human keratinocytes (HaCaT). Pre-treatment with lucidone (1–4 µM) significantly protects keratinocytes from UVA (15 J/...

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Bibliographic Details
Main Authors: You-Cheng Hseu, Yu-Cheng Tsai, Pei-Jane Huang, Ting-Tsz Ou, Mallikarjuna Korivi, Li-Sung Hsu, Show-Huei Chang, Chi-Rei Wu, Hsin-Ling Yang
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Journal of Functional Foods
Subjects:
Lucidone
Lindera erythrocarpa
UVA
ROS
Nrf2
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464614003259

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http://www.sciencedirect.com/science/article/pii/S1756464614003259

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