Rare APOA5 promoter variants associated with paradoxical HDL cholesterol decrease in response to fenofibric acid therapy[S]

Rare APOA5 promoter variants associated with paradoxical HDL cholesterol decrease in response to fenofibric acid therapy[S]

Individuals with mixed dyslipidemia, including high triglycerides (TGs) and low high density lipoprotein cholesterol (HDL-C), have increased risk for coronary events. We examined the effect of rare genetic variants in the APOA5 gene region on plasma HDL-C, apolipoprotein A-I (apoA-I), and TG respons...

Full description

Bibliographic Details
Main Authors: Ariel Brautbar, Maja Barbalic, Fengju Chen, John Belmont, Salim S. Virani, Steve Scherer, Robert A. Hegele, Christie M. Ballantyne
Format: Article
Language:English
Published: Elsevier 2013-07-01
Series:Journal of Lipid Research
Subjects:
apolipoproteins
cholesterol-lowering drugs
lipids
rare variants
fenofibric acid
high density lipoprotein
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520421455

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520421455

Similar Items