Compositional and Functional Differences in the Human Gut Microbiome Correlate with Clinical Outcome following Infection with Wild-Type Salmonella enterica Serovar Typhi

Compositional and Functional Differences in the Human Gut Microbiome Correlate with Clinical Outcome following Infection with Wild-Type Salmonella enterica Serovar Typhi

Insights into disease susceptibility as well as the efficacy of vaccines against typhoid and other enteric pathogens may be informed by better understanding the relationship between the effector immune response and the gut microbiota. In the present study, we characterized the composition (16S rRNA...

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Bibliographic Details
Main Authors: Yan Zhang, Arthur Brady, Cheron Jones, Yang Song, Thomas C. Darton, Claire Jones, Christoph J. Blohmke, Andrew J. Pollard, Laurence S. Magder, Alessio Fasano, Marcelo B. Sztein, Claire M. Fraser
Format: Article
Language:English
Published: American Society for Microbiology 2018-05-01
Series:mBio
Subjects:
16S rRNA gene profiling
Salmonella
immunization
metatranscriptomics
methanogens
microbiome
typhoid disease
Online Access:https://doi.org/10.1128/mBio.00686-18

Internet

https://doi.org/10.1128/mBio.00686-18

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