Current estimates for HIV-1 production imply rapid viral clearance in lymphoid tissues.

It has recently been estimated that a single HIV-1 infected cell produces between and more than viral particles over its life span. Since body-wide estimates of the ratio of free virus to productively infected cells are smaller than and much smaller than , individual virions must be cleared rapidly....

Full description

Bibliographic Details
Main Authors: Rob J De Boer, Ruy M Ribeiro, Alan S Perelson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2932679?pdf=render