The Aquaporin 5 −1364A/C Promoter Polymorphism Is Associated With Cytomegalovirus Infection Risk in Kidney Transplant Recipients

The Aquaporin 5 −1364A/C Promoter Polymorphism Is Associated With Cytomegalovirus Infection Risk in Kidney Transplant Recipients

Background: The aquaporin 5 (AQP5) −1364A/C promoter single nucleotide polymorphism affects key mechanisms of inflammation and immune cell migration. Thus, it could be involved in the pathogenesis of cytomegalovirus infection. Accordingly, we tested the hypothesis that the AQP5 promoter −1364A/C pol...

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Bibliographic Details
Main Authors: Tim Rahmel, Hartmuth Nowak, Katharina Rump, Björn Koos, Peter Schenker, Richard Viebahn, Michael Adamzik, Lars Bergmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Immunology
Subjects:
AQP5
single nucleotide polymorphism (SNP)
cytomegalovirus
immunosuppression
infection risk
kidney transplantation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02871/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02871/full

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