Toll-Like Receptor 4, but Not Neutrophil Extracellular Traps, Promote IFN Type I Expression to Enhance Th2 Responses to Nippostrongylus brasiliensis

Toll-Like Receptor 4, but Not Neutrophil Extracellular Traps, Promote IFN Type I Expression to Enhance Th2 Responses to Nippostrongylus brasiliensis

The induction of Th2 responses is thought to be multifactorial, and emerge from specific pathways distinct from those associated with antagonistic antibacterial or antiviral Th1 responses. Here, we show that the recognition of non-viable Nippostrongylus brasiliensis (Nb) in the skin induces a strong...

Full description

Bibliographic Details
Main Authors: Christophe Pellefigues, Shiau-Choot Tang, Alfonso Schmidt, Ruby F. White, Olivier Lamiable, Lisa M. Connor, Christiane Ruedl, Jurek Dobrucki, Graham Le Gros, Franca Ronchese
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Immunology
Subjects:
Nippostrongylus brasiliensis
helminth
dendritic cells
toll-like receptor 4
IFN-I
neutrophil extracellular traps
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01575/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01575/full

Similar Items