Clinical Resistome Screening of 1,110 Escherichia coli Isolates Efficiently Recovers Diagnostically Relevant Antibiotic Resistance Biomarkers and Potential Novel Resistance Mechanisms

Clinical Resistome Screening of 1,110 Escherichia coli Isolates Efficiently Recovers Diagnostically Relevant Antibiotic Resistance Biomarkers and Potential Novel Resistance Mechanisms

Multidrug-resistant pathogens represent one of the biggest global healthcare challenges. Molecular diagnostics can guide effective antibiotics therapy but relies on validated, predictive biomarkers. Here we present a novel, universally applicable workflow for rapid identification of antimicrobial re...

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Bibliographic Details
Main Authors: Carsten Volz, Jonas Ramoni, Stephan Beisken, Valentina Galata, Andreas Keller, Achim Plum, Andreas E. Posch, Rolf Müller
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Microbiology
Subjects:
functional metagenomics
antibiotic resistance
high-throughput screening
biomarkers
bioinformatics
biostatistics
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01671/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.01671/full

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