GSK461364A, a Polo-Like Kinase-1 Inhibitor Encapsulated in Polymeric Nanoparticles for the Treatment of Glioblastoma Multiforme (GBM)

GSK461364A, a Polo-Like Kinase-1 Inhibitor Encapsulated in Polymeric Nanoparticles for the Treatment of Glioblastoma Multiforme (GBM)

Glioblastoma Multiforme (GBM) is a common primary brain cancer with a poor prognosis and a median survival of less than 14 months. Current modes of treatment are associated with deleterious side effects that reduce the life span of the patients. Nanomedicine enables site-specific delivery of active...

Full description

Bibliographic Details
Main Authors: Praveena Velpurisiva, Brandon P. Piel, Jack Lepine, Prakash Rai
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Bioengineering
Subjects:
GSK461364A
Glioblastoma Multiforme
polymeric nanoparticles
cytotoxicity
enhanced permeability and retention
polo-like kinase inhibitor
oncology
oncomedicine
U-87 MG
Online Access:http://www.mdpi.com/2306-5354/5/4/83

Internet

http://www.mdpi.com/2306-5354/5/4/83

Similar Items