The replication machinery of LUCA: common origin of DNA replication and transcription
Abstract Origin of DNA replication is an enigma because the replicative DNA polymerases (DNAPs) are not homologous among the three domains of life, Bacteria, Archaea, and Eukarya. The homology between the archaeal replicative DNAP (PolD) and the large subunits of the universal RNA polymerase (RNAP)...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2020-06-01
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| Series: | BMC Biology |
| Online Access: | http://link.springer.com/article/10.1186/s12915-020-00800-9 |