Intranasal LPS-mediated Parkinson's model challenges the pathogenesis of nasal cavity and environmental toxins.

Accumulating evidence implicates the relationship between neuroinflammation and pathogenesis in idiopathic Parkinson's disease (iPD). The nose has recently been considered a gate way to the brain which facilitates entry of environmental neurotoxin into the brain. Our study aims to build a PD mo...

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Bibliographic Details
Main Authors: Qing He, Wenbo Yu, Jianjun Wu, Chan Chen, Zhiyin Lou, Qiong Zhang, Jian Zhao, Jian Wang, Baoguo Xiao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3826714?pdf=render