Quantitave and qualitative interferences of pentoxifillyne on hepatic Schistosoma mansoni granulomas: effects on extracellular matrix and eosinophil population

Quantitave and qualitative interferences of pentoxifillyne on hepatic Schistosoma mansoni granulomas: effects on extracellular matrix and eosinophil population

Mast cells and eosinophils actively participate in tissue repair and are prominent components of Schistosoma mansoni granulomas. Since pentoxifillyne (PTX) is an immunomodulatory and antifibrotic substance, we aimed to characterize, by morphological techniques, the effect of this drug on fibrosis de...

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Bibliographic Details
Main Authors: Luis Felipe Reis, Túlio Galvão Ventura, Sônia Oliveira Souza, Arturo Arana-Pino, Marcelo Pelajo-Machado, Mario José S Pereira, Henrique Leonel Lenzi, Maria José Conceição, Christina Maeda Takiya
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2001-09-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
mast cell
eosinophil
collagen
pentoxifylline
Schistosoma mansoni
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762001000900015

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762001000900015

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