Quantitave and qualitative interferences of pentoxifillyne on hepatic Schistosoma mansoni granulomas: effects on extracellular matrix and eosinophil population
Mast cells and eosinophils actively participate in tissue repair and are prominent components of Schistosoma mansoni granulomas. Since pentoxifillyne (PTX) is an immunomodulatory and antifibrotic substance, we aimed to characterize, by morphological techniques, the effect of this drug on fibrosis de...
Main Authors: | Luis Felipe Reis, Túlio Galvão Ventura, Sônia Oliveira Souza, Arturo Arana-Pino, Marcelo Pelajo-Machado, Mario José S Pereira, Henrique Leonel Lenzi, Maria José Conceição, Christina Maeda Takiya |
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Format: | Article |
Language: | English |
Published: |
Instituto Oswaldo Cruz, Ministério da Saúde
2001-09-01
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Series: | Memórias do Instituto Oswaldo Cruz. |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762001000900015 |
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