MiR-223 regulates autophagy associated with cisplatin resistance by targeting FBXW7 in human non-small cell lung cancer

MiR-223 regulates autophagy associated with cisplatin resistance by targeting FBXW7 in human non-small cell lung cancer

Abstract Background Cisplatin is widely used as a first-line treatment for non-small cell lung cancer (NSCLC), but chemoresistance remains a major clinical obstacle for efficient use. As a microRNA, miR-223 was reported to promote the doxorubicin resistance of NSCLC. However, whether miR-223 is also...

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Bibliographic Details
Main Authors: Hui Wang, Jiabin Chen, Shufen Zhang, Xiaoxiao Zheng, Shangzhi Xie, Jiayan Mao, Ying Cai, Xuemei Lu, Liqiang Hu, Jian Shen, Kequn Chai, Wei Chen
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Cancer Cell International
Subjects:
MiR-223
Chemoresistance
Non-small cell lung cancer (NSCLC)
Autophagy
FBXW7
Online Access:http://link.springer.com/article/10.1186/s12935-020-01284-x

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http://link.springer.com/article/10.1186/s12935-020-01284-x

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