Luteolin Inhibits Vascular Smooth Muscle Cell Proliferation and Migration by Inhibiting TGFBR1 Signaling

Luteolin Inhibits Vascular Smooth Muscle Cell Proliferation and Migration by Inhibiting TGFBR1 Signaling

Vascular smooth muscle cell (VSMC) proliferation and migration play a critical role in the development of arterial remodeling during various vascular diseases including atherosclerosis, hypertension, and related diseases. Luteolin is a food-derived flavonoid that exerts protective effects on cardiov...

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Bibliographic Details
Main Authors: Yu-Ting Wu, Ling Chen, Zhang-Bin Tan, Hui-Jie Fan, Ling-Peng Xie, Wen-Tong Zhang, Hong-Mei Chen, Jun Li, Bin Liu, Ying-Chun Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Pharmacology
Subjects:
luteolin
vascular smooth muscle cell
proliferation
migration
TGFBR1
Smad2/3
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01059/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.01059/full

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